Science-Studies

2017

Maternal supplementation with fish oil might have prophylactic potential for long-term prevention of asthma in offspring.

Higher Omega-3: omega-6 ratio is important for fetal health.

2016

Supplementation with omega-3 fatty acids in the third trimester of pregnancy reduced the risk of persistent wheeze or asthma and infections of the lower respiratory tract in offspring.

Omega-3 supplementation during either pregnancy or infancy improves child neurodevelopment.

2015

Supplementing pregnant women with DHA could lead to significant cost savings.

DHA may improve transplacental iron homeostasis and therefore may enhance iron transfer and boost neonates iron stores at delivery.

Supplementation of overweight/obese pregnant women with omega-3 fatty acids for >25 weeks reduced inflammation in maternal adipose and the placental tissue.

2013

A low omega-3 index in late pregnancy was associated with higher depression score three months postpartum.

2007

Maternal seafood consumption of more than 340 g per week in pregnancy has beneficial effects on child development (ALSPAC-study).

2003

Maternal omega-3 supplementation potentially reduces subsequent infant allergy.

Maternal intake of omega-3 during pregnancy and lactation may be favorable for later mental development of children.

Supplementation of DHA can contribute in optimizing visual development in infants.

2002

Lower DHA content in mothers' milk was associated with higher rates of postpartum depression.

2018

Omega-3 fatty acids might be treatment option for ADHD. There is meta-analytical evidence that omega-3 supplementation monotherapy improves clinical symptoms and cognitive performances in children and adolescents with ADHD, and that these youth have a deficiency in omega-3 levels.

2016

Omega-3 fatty acids may have small effects on emotional lability (characterized by irritable moods with volatile and changeable emotions) and oppositional behavior in subgroups of children with ADHD.

Possible association between blood Omega-3 Index and cognition in typically developing adolescents.

2015

Omega-3 improves parent-rated attention in children with and without ADHD.

2011

Omega-3 fatty acid supplementation, particularly with higher doses of eicosapentaenoic acid (EPA), was modestly effective in the treatment of ADHD.

2010

EPA supplementation improves teacher-rated behavior and oppositional symptoms in children with ADHD.

2017

Omega-3 fatty acids may reduce heart patients’ hospital stay.

Supplementation with EPA+DHA may be associated with reducing coronary heart disease risk, with a greater benefit observed among higher-risk populations.

Interesting science advisory update on ‘Fish oil for patients with documented coronary heart disease’

2016

EPA and DHA can reduce blood pressure.

2015

Omega-3 fatty acids have the potential to beneficially impact arterial wall remodeling and cardiovascular outcomes by targeting arterial wall stiffening and endothelial dysfunction.

Omega-3 fatty acids have been shown to be associated with reductions in plasma triglyceride levels of approximately 25%- 34%.

Omega-3 fatty acids have beneficial effects on circulating triglyceride levels in normolipidemic to borderline hyperlipidemic, otherwise healthy, individuals.

2007

European and American Cardiac Societies incorporated EPA and DHA into treatment guidelines for myocardial infarction, prevention of cardiovascular disease, treatment of ventricular arrhythmias and prevention of sudden cardiac death.

2004

The Omega-3 Index was inversely associated with risk for coronary heart disease mortality. An Omega-3 Index of > or = 8% was associated with the greatest cardioprotection, whereas an index of < or = 4% was associated with the least.

2003

Atherosclerotic plaques readily incorporate omega-3 fatty acids from fish-oil supplementation, inducing changes that can enhance stability of atherosclerotic plaques.

1999

Treatment with omega-3 fatty acids significantly lowered the risk of cardiovascular death after myocardial infarction (GISSI-Prevenzione trial).

2017

Omega-3 fatty acids promote amyloid-β clearance from the brain through mediating the function of the glymphatic system.

2016

Omega-3 fatty acids, especially higher doses EPA, may be beneficial in major depressive disorder. Patients taking antidepressants benefit most.

2015

Omega-3 fatty acids supplementation may attenuate oxidative stress mechanisms, thereby offering benefits for depression prevention.

2014

The use of omega-3 fatty acids, EPA rather than DHA, improves depressive symptoms in patients with and without diagnosis of major depressive disorder.

2012

Omega-3 intake may reduce depressive symptoms in older adults with mild cognitive impairment.

2009

EPA may be more efficacious than DHA in treating depression.

2008

Supplementation with 1 gram EPA daily for 8 weeks has equal therapeutic effects in major depressive disorder than 20 mg fluoxetine/day.

2003

A higher ratio of omega-3 to omega-6 fatty acids in erythrocyte membranes was associated with a lower risk of cognitive decline (EVA-study).

2017

Omega-3 fatty acids alone or in combination with ɤ-Linolenic Acid (GLA) exerted significant clinical benefits in patients with rheumatoid arthritis.

2015

Daily supplementation with 1 – 2 g fish oil had significant efficacy to improve knee performance in mild to moderate stages of knee osteoarthritics patients.

2003

A daily dose of 1.6 gram EPA improves joint symptoms in patients with rheumatoid arthritis.

2002

Intravenous omega-3 fatty acid administration causes reduction of psoriasis, which may be related to changes in inflammatory eicosanoid generation.

2015

Omega-3 fatty acids may improve symptoms of dry eyes in contact lens wearers.

Omega-3 fatty acids may improve symptoms of dry eyes associated with prolonged exposure to computer screens.

2005

DHA is a major structural lipid of retinal photoreceptors. Omega-3 fatty acids may act in a protective role against ischemia-, light-, oxygen-, inflammatory-, and age-associated pathology of the retina.

2003

DHA protects retina photoreceptors from oxidative stress.

2017

Omega-3 fatty acids may be beneficial for neuropathy in type 1 diabetes.

2016

Fish oil may alleviate muscle soreness experienced after resistance training in young untrained females.

2015

Omega-3 fatty acid supplementation improves aspects of neuromuscular function and performance in male athletes.

Omega-3 fatty acids supplementation improves endothelial function and maximal oxygen uptake in endurance-trained athletes.

2017

Omega-3 fatty acids correlate with gut microbiome diversity in women.

2015

Omega-3 fatty acid EPA may help commensal bacteria in the human gut.